16% of Adults Have Diabetes; Compounded Semaglutide Deaths; Testosterone Tx Surge

An estimated 16% of U.S. adults have diabetes, and 4.5% of cases are undiagnosed, according to a CDC report.

Supplementation with cholecalciferol (vitamin D3) and calcium reduced blood pressure in a 1-year randomized trial of older patients with overweight. (Journal of the Endocrine Society)

Novo Nordisk leadership acknowledged reports of mortality and hospitalizations among people taking compounded copies of semaglutide (Wegovy, Ozempic). (CNN)

Among postmenopausal women who had received denosumab (Prolia) for 2 or more years, sequential therapy with zoledronate did not prevent loss of bone mineral density in the lumbar spine in the first year, a randomized trial showed. (JAMA Network Open)

Few state Medicaid programs cover GLP-1 drugs for obesity, citing the agents’ high cost, a new KFF analysis found.

Diabetes and weight-loss drug tirzepatide (Mounjaro, Zepbound) was listed as a contributing factor in the death of a 58-year-old nurse from Scotland who died of multiple organ failure, septic shock, and pancreatitis. (BBC)

Lower income was tied to higher all-cause mortality among younger adults with type 2 diabetes in a South Korean cohort study. (JAMA Network Open)

Social media influencers may be driving a surge in testosterone replacement therapy in middle-age women. (NBC News)

Levels of plasma F2-isoprostanes — a reliable oxidative stress marker — was associated with an increased fracture risk in type 2 diabetes patients, an observational cohort study showed. (Journal of Clinical Endocrinology & Metabolism)

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