Best Diets for GI Conditions; Twin Pregnancies With IBD; Mortality Risk in MAFLD

U.S. News released its list of best diets for 2025: the low-FODMAP diet landed on top for irritable bowel syndrome and the Mediterranean diet ranked first for diverticulitis, fatty liver disease, and gut health.

Meanwhile, aspirin use in patients with diabetes was linked with a lower risk of pancreatic cancer and cancer mortality, a Hong Kong study found. (Gut)

Norovirus outbreaks are surging in the U.S. on land and sea. (NPR)

Compared with twin pregnancies among healthy controls, twin pregnancies in women with inflammatory bowel disease (IBD) were associated with an increased risk for preterm birth, small for gestational age, and low birth weight. (Clinical Gastroenterology and Hepatology)

And pregnancies in IBD patients with a stoma proved feasible in Dutch women, though with manageable complications. (Inflammatory Bowel Diseases)

Placebo-controlled phase I data showed that a novel PNPLA3 antisense oligonucleotide (AZD2693) reduced hepatic steatosis in patients with metabolic dysfunction-associated steatohepatitis. (Journal of Hepatology)

The EU-approved diagnostic tool LiverPRO — which relies on age and routinely captured laboratory values — can identify significant liver fibrosis and stiffness and predict liver-related events in patients with steatotic liver disease, prospective data showed. (Lancet Gastroenterology & Hepatology)

And the Body Roundness Index and Systemic Immune-Inflammation Index can predict mortality risk in patients with metabolic dysfunction-associated fatty liver disease (MAFLD). (Scientific Reports)

In a phase II trial, induction therapy with the investigational S1P1 receptor 1 modulator tamuzimod for moderately-to-severely active ulcerative colitis (UC) was well-tolerated and associated with a week-13 clinical remission rate of 28% versus 11% with placebo. (Lancet Gastroenterology & Hepatology)

Clinical Gastroenterology and Hepatology reviewed the use of point-of-care ultrasound for gastroenterologists and hepatologists.

While immunotherapy prior to liver transplant in patients with hepatocellular carcinoma and its association with subsequent graft failure was reviewed by theJournal of Hepatology.

A 32-year-old British woman underwent a successful liver transplantation for advanced colorectal cancer that had spread to the organ, the first such case in the U.K. (BBCNews)