Brain Aging Biomarkers; Midlife Anxiety and Dementia Risk; Who Chose Assisted Dying?

Researchers identified 13 proteins that predicted how quickly or slowly a person’s brain aged. (Nature Aging)

Midlife anxiety was common decades before people developed dementia, the Norwegian HUNT study showed. (Alzheimer’s & Dementia)

Investigational tavapadon met its primary endpoint in a flexible dosing phase III trial of Parkinson’s disease, showing improvements from baseline in symptoms and quality of life scores at week 26, AbbVie announced.

The p38MAP kinase alpha enzyme inhibitor neflamapimod missed its primary and secondary endpoints in a phase II study of dementia with Lewy bodies, CervoMed said.

Neurodegeneration in the cortical sulcus was a feature of chronic traumatic encephalopathy and was associated with repetitive head impacts, autopsy data showed. (Acta Neuropathologica)

People with amyotrophic lateral sclerosis or cancer were more likely than others to choose assisted dying regardless of where they lived, an analysis found. (JAMA Internal Medicine)

Dementia risk was higher among former soccer players in Scotland despite modifiable dementia risk factors being lower or no different than population controls. (JAMA Network Open)

Diverse cell types in the brain parenchyma contribute to neuroinflammation in Alzheimer’s disease, a review showed. (Nature Reviews Immunology)

The Washington Post highlighted award-winning images documenting a grandmother’s challenges with Alzheimer’s.

CNN looked at Michael J. Fox’s fight against Parkinson’s.

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