Brain Blood Flow and Alzheimer’s; Neuroscientist Runs for Congress; MS Drug Win

Brain blood flow was associated with established Alzheimer’s disease neuroimaging measures, cross-sectional data showed. (Alzheimer’s & Dementia)

Years of playing American football correlated with cognitive and neuropsychiatric scores later in life, a large cross-sectional study showed. (JAMA Network Open)

Neuroscience professor and autism researcher Sam Wang, PhD, of Princeton University, is running for Congress. (The Transmitter)

The HHS Office of Inspector General said Colorado made at least $77 million in Medicaid overpayments for applied behavior analysis services to treat children with autism and other developmental disabilities.

Antibiotic-induced gut changes may aid recovery from traumatic brain injury, a mouse study suggested. (Communications Biology)

The FDA said that data from a phase I/II study that included external controls were not sufficient to decide on the investigational gene therapy AMT-130 for Huntington’s disease and recommended a sham surgery-controlled trial, uniQure reported.

The investigational Bruton’s tyrosine kinase inhibitor fenebrutinib reduced annualized relapse rates by 51% compared with teriflunomide (Aubagio) in the phase III FENhance 1 trial of relapsing multiple sclerosis (MS), Roche announced. The data followed positive results from another phase III trial of fenebrutinib in relapsing MS and one in primary progressive MS.

Gabapentin improved symptoms in a patient who appeared to have restless arm syndrome, an upper limb variant of restless leg syndrome, a case report documented. (Case Reports in Neurological Medicine)

Paternal use of valproate within 90 days before conception was not associated with an increased risk of neurodevelopmental disorders in offspring, data from two cohorts showed. (NEJM Evidence)

Actor Michael J. Fox shared his journey since his Parkinson’s disease diagnosis in 1991. (People)

The Guardian published an extract from the newly published memoir by actress Christina Applegate, who was diagnosed with MS in 2021.