Sunday, June 1, 2025
News Health
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health
No Result
View All Result
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health
No Result
View All Result
HealthNews
No Result
View All Result
Home Health News

Corcept’s Ovarian Cancer Drug Cuts Disease Progression in Study, Shares Jump

March 31, 2025
in Health News
Share on FacebookShare on Twitter


(Reuters) -Corcept Therapeutics said on Monday its experimental drug in combination with chemotherapy helped delay progression of a type of ovarian cancer in a late-stage trial.

Shares of Corcept surged about 84% to a record high of $100.29, on track to add about $4.82 billion to the company’s market capitalization, if gains hold.

The drug, relacorilant, in combination with chemotherapy, reduced the risk of cancer progression by 30% in ovarian cancer patients who were resistant to platinum-based chemotherapy treatments, compared with those on chemotherapy alone, meeting one of the main goals of the study, Corcept said.

In the trial that enrolled 381 patients, those who received the drug combination lived one month longer without their disease worsening, compared with those who received chemotherapy alone.

The drug combination also showed significant improvement in overall survival, the second main goal, with patients on the treatment living for an average of 16 months, compared with 11.5 months for those on chemotherapy alone.

Overall survival indicates the period of time patients lived after their diagnosis or the start of the treatment.

The drug was well-tolerated with no new safety concerns, Corcept said, adding that it planned to present full study results in the coming months and file a marketing application in the U.S. in the third quarter of this year.

The success of the trial will significantly build on Corcept’s cortisol-modulating platform and commercial success, if approved, Canaccord Genuity analyst Edward Nash said.

Nash estimates peak sales of $1.3 billion for relacorilant in platinum-resistant ovarian cancer by 2036.

Relacorilant, an oral therapy, works by blocking cortisol, a stress hormone, which helps tumors resist chemotherapy, according to the company.

Current treatment options for platinum-resistant ovarian cancer include AbbVie’s Elahere and Roche’s Avastin.

Ovarian cancer affects an estimated 238,484 women in the U.S. each year, and about 20,000 of these cases annually are classified as platinum-resistant, according to the National Cancer Institute

(Reporting by Kamal Choudhury, Padmanabhan Ananthan and Mariam Sunny in Bengaluru; Editing by Shounak Dasgupta and Anil D’Silva)



Source link : https://www.medscape.com/s/viewarticle/corcepts-ovarian-cancer-drug-meets-main-goal-late-stage-2025a10007nk?src=rss

Author :

Publish date : 2025-03-31 12:18:00

Copyright for syndicated content belongs to the linked Source.

Previous Post

Vestibular Therapy in ED Shows Promise for Dizziness

Next Post

Chewing Gum Contributes to Microplastic Ingestion

Related Posts

Health News

Can New Biomarker Help Identify High-Risk DLBCL Patients?

June 1, 2025
Health News

Adjuvant Immunotherapy Ups Survival in dMMR Colon Cancer

June 1, 2025
Health News

Colon Cancer Patients Live Longer With Exercise Prescription

June 1, 2025
Health News

Don’t Dismiss the Possibility of Colorectal Cancer in Young Adult Patients

June 1, 2025
Health News

Which Class of ER Degrader Is Better?

June 1, 2025
Health News

Perioperative Durvalumab Plus FLOT Boosts EFS in Resectable Gastric/GEJ Cancer

June 1, 2025
Load More

Can New Biomarker Help Identify High-Risk DLBCL Patients?

June 1, 2025

Adjuvant Immunotherapy Ups Survival in dMMR Colon Cancer

June 1, 2025

Colon Cancer Patients Live Longer With Exercise Prescription

June 1, 2025

Don’t Dismiss the Possibility of Colorectal Cancer in Young Adult Patients

June 1, 2025

Which Class of ER Degrader Is Better?

June 1, 2025

Perioperative Durvalumab Plus FLOT Boosts EFS in Resectable Gastric/GEJ Cancer

June 1, 2025

Trial Changes First-Line Approach for Most Common Breast Cancer Subtype

June 1, 2025

Viral TikTok Trend for Weight Loss Is Harmful for Health

June 1, 2025
Load More

Categories

Archives

June 2025
MTWTFSS
 1
2345678
9101112131415
16171819202122
23242526272829
30 
« May    

© 2022 NewsHealth.

No Result
View All Result
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health

© 2022 NewsHealth.

Go to mobile version