Tuesday, July 1, 2025
News Health
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health
No Result
View All Result
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health
No Result
View All Result
HealthNews
No Result
View All Result
Home Health News

Gender Differences With Low-Dose Minoxidil Side Effects

July 1, 2025
in Health News
Share on FacebookShare on Twitter


TOPLINE:

A series of retrospective studies reported that women treated with low-dose oral minoxidil (LDOM) experience orthostatic symptoms more frequently than men, despite normal blood pressure (BP) readings.

METHODOLOGY:

  • Researchers reported findings from multiple retrospective studies, which included patients with androgenetic alopecia (AGA) who received LDOM.
  • Researchers also conducted a pooled analysis of five studies.
  • Studies analyzed doses, changes in BP, and adverse events (AEs) in men and women.

TAKEAWAY:

  • In a retrospective cohort study of 151 patients (59% women), LDOM was well-tolerated across age and sex groups; average doses for women and men were similar between women (1.9 mg/d for women and 2.1 mg/d for men; P = .32), with no clinically significant changes in BP.
  • In another study of 128 patients (71.1% women), researchers noted no significant BP changes overall, except a minor diastolic BP reduction in men (-3.1 mm Hg; P = .01); women received lower doses than men (average, 1.265 mg/d vs 2.179 mg/d).
  • In the pooled analysis that included the four other studies (n = 2409; 93.7% women), women were two to three times more likely than men to report AEs despite receiving a dose of < 1 mg/d and often with no measurable BP changes, suggesting BP monitoring may not fully reflect sex-specific tolerability differences.
  • In a study of 310 patients with AGA (53.2% women), women were prescribed lower average doses than men (1.8 vs 2.2 mg/d; P < .001) but reported dizziness/lightheadedness more frequently (22.4% vs 5.5%; P < .001).

IN PRACTICE:

“Presence of hypotensive symptoms without measurable hypotension raises the possibility that symptom perception or anxiety-related responses to cardiovascular sensations may influence tolerability, especially in women,” the study authors wrote. “Further research is warranted to explore the physiologic and psychologic mechanisms underlying these sex-based differences, which could inform more personalized dosing and monitoring strategies,” they added.

SOURCE:

The study was conducted by Michael M. Ong, BS, Weill Cornell Medicine, and Shari Lipner, MD, Department of Dermatology, Weill Cornell Medicine, New York City, and was published online on June 26 in the Journal of the American Academy of Dermatology.

LIMITATIONS:

The reliance solely on BP measurements may not fully capture the range of vascular sensitivity experienced by patients.

DISCLOSURES:

The study received no funding. Lipner disclosed serving as a consultant for Moberg Pharma and BelleTorus Corporation.

This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.



Source link : https://www.medscape.com/viewarticle/aga-gender-differences-low-dose-minoxidil-side-effects-2025a1000hhe?src=rss

Author :

Publish date : 2025-07-01 06:50:00

Copyright for syndicated content belongs to the linked Source.

Previous Post

Headache Common After Hemorrhagic Stroke, Often Overlooked

Next Post

Should You Do ‘Away Rotations’ As a Fourth-Year Med Student?

Related Posts

Health News

Gastric Procedure Alleviates GERD Symptoms in Obesity

July 1, 2025
Health News

Surgery Boosts Language Recovery in Post-Stroke Aphasia

July 1, 2025
Health News

Telehealth vs In-Person ADHD Prescribing: Which is Safest?

July 1, 2025
Health News

Should You Do ‘Away Rotations’ As a Fourth-Year Med Student?

July 1, 2025
Health News

Headache Common After Hemorrhagic Stroke, Often Overlooked

July 1, 2025
Health News

Ablation Still Best Option When Patient Has AF and Obesity

July 1, 2025
Load More

Gastric Procedure Alleviates GERD Symptoms in Obesity

July 1, 2025

Surgery Boosts Language Recovery in Post-Stroke Aphasia

July 1, 2025

Telehealth vs In-Person ADHD Prescribing: Which is Safest?

July 1, 2025

Should You Do ‘Away Rotations’ As a Fourth-Year Med Student?

July 1, 2025

Gender Differences With Low-Dose Minoxidil Side Effects

July 1, 2025

Headache Common After Hemorrhagic Stroke, Often Overlooked

July 1, 2025

Ablation Still Best Option When Patient Has AF and Obesity

July 1, 2025

13 Cancers in One Blood Test — but 75% False Alarms

July 1, 2025
Load More

Categories

Archives

July 2025
MTWTFSS
 123456
78910111213
14151617181920
21222324252627
28293031 
« Jun    

© 2022 NewsHealth.

No Result
View All Result
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health

© 2022 NewsHealth.

Go to mobile version