HEARTS Act Gets Senate Vote; New Myocarditis Classes; Aftermath of PAD Device Scare

The office of Senate Majority Leader Chuck Schumer (D-N.Y.) said that this week he will bring the HEARTS Act, the bipartisan legislation to equip schools with automatic external defibrillators and provide CPR training to laypeople, to the Senate floor for a vote on it becoming law.

A novel four-stage myocarditis classification was released in the American College of Cardiology’s new Expert Consensus Decision Pathway for the diagnosis and management of acute myocarditis in adults.

Unlike the steady or slightly downward trends in the prevalence of heart failure in general populations around the world, the burden of heart failure is still increasing in young people ages 10-24 years. (eClinicalMedicine)

In younger generations of Americans in particular, total cholesterol and triglyceride level improvements are decelerating on a population level. Adverse trends in glucose are all the while mediated partially by rising BMIs. (JAMA Network Open)

Positive topline results for the lipid-lowering agent obicetrapib in the phase III BROADWAY trial were announced by NewAmsterdam.

Cohort studies suggest that different sources of sugar have different effects on cardiovascular risk — the occasional sweet treat being associated with better outcomes than no treats at all. (Frontiers in Public Health)

Proinflammatory diets may have varying ties to cardiovascular risk in women, depending on their history of adverse pregnancy outcomes such as preterm birth and gestational diabetes. (Journal of the American Heart Association)

For primary care patients, a person’s estimated “heart age” should not be conflated with a cardiovascular risk score, according to an observational study. (Heart)

Safety fears surrounding paclitaxel-coated peripheral arterial revascularization devices in 2018 were followed by a marked decrease in use of them and an accompanying increase in mortality. (Journal of the American College of Cardiology)

Gene variants associated with increasing transthyretin tetramer destabilization were indeed linked to all-cause and cardiovascular mortality in a Danish cohort study. (JAMA Cardiology)

On the basis of genetic susceptibility, some people may be particularly vulnerable to the air pollution-ventricular arrhythmia relationship. (European Journal of Preventive Cardiology)

A protein panel showed promise for detecting subclinical, anthracycline-associated cardiomyopathy among survivors of childhood cancer. (JACC: CardioOncology)

Biologic treatment of psoriasis was associated with survival and cardiovascular benefits, relative to traditional medications or apremilast (Otezla), in a retrospective study. (eBioMedicine)

Japanese researchers made a case for more adjunctive treatments tackling hemodynamic impairment after stroke thrombectomy, given their case series showing that successful recanalization does not always result in immediate tissue reperfusion. (Stroke)

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