Sunday, August 31, 2025
News Health
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health
No Result
View All Result
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health
No Result
View All Result
HealthNews
No Result
View All Result
Home Health News

Iron Therapy Can Treat Anaemia in Kidney Transplant Kids

July 31, 2025
in Health News
Share on FacebookShare on Twitter


TOPLINE:

In paediatric kidney transplant recipients with iron deficiency, with or without anaemia, intravenous ferric carboxymaltose therapy was safe and led to significant increases in haemoglobin levels at as early as 1 month after the first dose, with improvements being maintained for up to 12 months.

METHODOLOGY:

  • Researchers conducted a retrospective cohort study to assess the safety and effectiveness of intravenous ferric carboxymaltose for treating iron deficiency and anaemia in paediatric kidney transplant recipients.
  • They included 15 patients with kidney transplants and iron deficiency, with or without anaemia (mean age, 15.4 years; 60% girls), who received intravenous ferric carboxymaltose after the failure of first-line oral iron therapy; 13 patients received two doses 30 days apart, and two received a single dose.
  • The median post-transplant follow-up duration was 41.8 months.
  • The primary outcome was changes from baseline in haemoglobin, transferrin saturation, and ferritin levels measured at multiple timepoints for up to 12 months post-treatment; secondary outcomes included changes in serum iron and phosphorus levels and assessment of adverse drug reactions.

TAKEAWAY:

  • Haemoglobin levels increased significantly from baseline after treatment with ferric carboxymaltose at 1, 3, 6, and 12 months (P < .05 for all timepoints).
  • A significant increase in ferritin levels was observed at 1, 3, and 6 months (P < .05), but not at 12 months.
  • Serum iron levels increased significantly at 1 and 3 months after treatment, and transferrin saturation improved after 30 days — even in patients whose saturation did not reach 20%.
  • Phosphate levels remained stable throughout the follow-up period, with no cases of hypophosphataemia observed. No adverse drug reactions were reported.

IN PRACTICE:

“Our data support the past evidence on the use of FCM [ferric carboxymaltose] in pediatric patients with CKD [chronic kidney disease], adding new insight on patients with successful KT [kidney transplant] in follow-up,” the authors wrote.

SOURCE:

This study was led by Diletta Domenica Torres, “Giovanni XXIII” Hospital, Bari, Italy. It was published online on July 26, 2025, in Pediatric Nephrology.

LIMITATIONS:

The study’s retrospective design and the small sample size were notable limitations of this study. Additionally, selection bias may have occurred, and reporting of adverse events may have been incomplete or underestimated.

DISCLOSURES:

This study did not report any source of funding. The authors declared having no conflicts of interest.

This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.



Source link : https://www.medscape.com/viewarticle/iron-therapy-can-treat-anaemia-kidney-transplant-kids-2025a1000k04?src=rss

Author :

Publish date : 2025-07-31 12:00:00

Copyright for syndicated content belongs to the linked Source.

Previous Post

Is Early Immunotherapy a Game Changer?

Next Post

Complex Medical Conditions Drive Children’s Mental Health

Related Posts

Health News

Texas Bill Would Let Residents Sue Out-of-State Abortion Pill Providers

August 31, 2025
Health News

Baby dies of whooping cough after mother not vaccinated while pregnant

August 31, 2025
Health News

County Durham mother’s vaccination plea after ‘terrifying’ measles

August 31, 2025
Health News

Doctors Dismissed Her Symptoms for Years Before Lyme Disease Diagnosis

August 31, 2025
Health News

The trade in US body parts that’s completely legal

August 30, 2025
Health News

Remote ECG Screening Ups AF Detection ‘Modestly’

August 30, 2025
Load More

Texas Bill Would Let Residents Sue Out-of-State Abortion Pill Providers

August 31, 2025

Baby dies of whooping cough after mother not vaccinated while pregnant

August 31, 2025

County Durham mother’s vaccination plea after ‘terrifying’ measles

August 31, 2025

Doctors Dismissed Her Symptoms for Years Before Lyme Disease Diagnosis

August 31, 2025

The trade in US body parts that’s completely legal

August 30, 2025

Remote ECG Screening Ups AF Detection ‘Modestly’

August 30, 2025

Year of Low-Dose DOAC Slashes Recurrence After Provoked VTE

August 30, 2025

Who Left the CDC This Week?

August 30, 2025
Load More

Categories

Archives

August 2025
MTWTFSS
 123
45678910
11121314151617
18192021222324
25262728293031
« Jul    

© 2022 NewsHealth.

No Result
View All Result
  • Health News
  • Hair Products
  • Nutrition
    • Weight Loss
  • Sexual Health
  • Skin Care
  • Women’s Health
    • Men’s Health

© 2022 NewsHealth.

Go to mobile version