TAVR’s Win in Women; Chest Pressure During Cardioversion; Doc Goes to Space

The RHEIA trial, which found transcatheter aortic valve replacement (TAVR) superior to surgery for women, was among the highlights of the European Society of Cardiology (ESC) congress.

Also at ESC was OCCUPI, which showed that optimal coherence tomography was better than angiography for guiding stent implantation during percutaneous coronary intervention in patients with complex coronary lesions.

Single measurements of cholesterol in young adulthood are predictive of cumulative exposure by age 40, which is then predictive of cardiovascular events later in life. (Journal of the American College of Cardiology)

Applying chest pressure during cardioversion failed to improve the efficacy of cardioversion in a randomized trial. (JACC: Clinical Electrophysiology)

According to an individual patient-level meta-analysis, percutaneous active mechanical circulatory support devices were more harmful than beneficial for people with acute myocardial infarction-related cardiogenic shock — unless they were patients with ST-elevation cardiogenic shock without risk of hypoxic brain injury. (Lancet)

Heart attack survivors demonstrated effects of intensive lipid-lowering therapy with alirocumab (Praluent) at the lesion level. (JAMA Cardiology)

For patients with heart failure and secondary mitral regurgitation with stubborn symptoms, transcatheter edge-to-edge repair was clinically noninferior to mitral valve surgery in the MATTERHORN trial. (New England Journal of Medicine)

Long-term safety and efficacy of mavacamten (Camzyos) in patients with obstructive hypertrophic cardiomyopathy were supported by the MAVA-LTE open-label extension study of EXPLORER-HCM. (European Heart Journal)

In Nigeria, there was better screening for peripartum cardiomyopathy when artificial intelligence (AI) analysis was applied to digital stethoscope and 12-lead ECG results. (Nature Medicine)

Renata Medical said the FDA approved its Minima Growth Stent, designed to be re-expanded as a child grows, for stenosis in the aorta or pulmonary arteries.

Experienced journal leaders could not distinguish AI- from human-written essays on stroke any better than a coin toss. (Stroke)

A Q&A with Vanderbilt cardiologist Eiman Jahangir, MD, MPH, who briefly went to space through the Blue Origin company owned by Jeff Bezos. (The Tennessean)

Uruguayan soccer player Juan Izquierdo reportedly died from cardiac arrest 5 days after he collapsed during a match in Brazil. (ESPN)

A senior cardiologist suspended from his job in Australia during an investigation into alleged bullying can return to work following an out of court settlement with Canberra Health Services. (Australian Broadcasting Corporation)

Zibotentan was a flop for microvascular angina in a small crossover randomized trial. (Circulation)