Your Brain on Mars; Differential Dementia Diagnosis by AI; ALS Gene Identified

More work is needed to mitigate the effects of long spaceflights on the central nervous system before humans travel to Mars, experts concluded. (Lancet Neurology)

A communication pathway between the central and peripheral nervous system identified in a mouse model of migraine may explain the relationship between aura and headache. (Science)

An artificial intelligence model created for differential dementia diagnosis distinguished between various dementia etiologies, exceeding neurologist-only evaluations in some cases. (Nature Medicine)

Investigational buntanetap improved motor and nonmotor activities in subgroups of Parkinson’s disease patients in a phase III trial, drugmaker Annovis said.

GUIDE, a Medicare pilot program that gives families of people with dementia an on-call care coordinator, will start this month. (NPR)

Researchers identified a pathogenic mutation in ARPP21 in people with amyotrophic lateral sclerosis (ALS) who lived in Spain. (Journal of Neurology, Neurosurgery, and Psychiatry)

Novel imaging showed persistent immune activation in the gut wall and spinal cord of long COVID patients with brain fog and fatigue. (Science Translational Medicine)

A writer looked at how Alzheimer’s disease unraveled his wife’s creative brain in her 40s. (The Guardian)

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