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Best Exercise Timing; GLP-1 Pill’s Heart Safety; Pop Star’s Cardiovascular Illness

April 21, 2026
in Health News
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A small trial suggested that timing exercise to match body clock chronotype enhanced cardiometabolic and sleep-related outcomes. (Open Heart)

The Society of Thoracic Surgeons published its new guideline for preventing and treating new-onset postoperative atrial fibrillation after cardiac surgery. (Annals of Thoracic Surgery)

Rapid Medical announced FDA clearance of the Tigertriever 25 thrombectomy device — designed specifically for large clot burdens in proximal vessels — for the treatment of large vessel occlusion stroke.

Landiolol (Rapiblyk) got expanded FDA approval for use in children with supraventricular tachycardia, according to AOP Health.

Stereotactic arrhythmia radioablation was associated with a lower burden of refractory ventricular tachycardia, based on registry analysis. (European Heart Journal)

The cardiovascular safety of the oral GLP-1 drug orforglipron (Foundayo) was reaffirmed in updated results from the ACHIEVE-4 study, Eli Lilly announced.

The C-reactive protein-triglyceride-glucose index may be a useful biomarker for identifying individuals at elevated risk of subclinical atherosclerosis, according to a longitudinal cohort study. (Clinical Cardiology)

Prediabetes was linked to incident atrial fibrillation in a large meta-analysis. (European Journal of Preventive Cardiology)

Pregnancy and the first year postpartum are high-opportunity periods to optimize women’s cardiovascular health, per a report from the National Academies of Sciences, Engineering, and Medicine.

The PROMISE model was developed to predict recurrent ischemic stroke risk in patients with symptomatic intracranial atherosclerotic stenosis. (Lancet Digital Health)

FDA 510(k) clearance was given to Protaryx Medical’s transseptal puncture device that provides left-heart access during cardiac interventions.

In the sham-controlled ORBITA-CTO trial, percutaneous coronary intervention for coronary chronic total occlusion provided real relief from angina. (Journal of the American College of Cardiology)

Cardiac fibrosis was implicated in particularly poor outcomes in people with severe aortic stenosis, and with specific cardiomyopathy etiologies visible on noninvasive imaging in people with heart failure. (JAMA Cardiology)

Genetic intervention showed promise for a rare, currently untreatable inherited cardiomyopathy, in a preclinical study. (Nature Cardiovascular Research)

Patients with hypertrophic cardiomyopathy (HCM) appear to be predisposed to infective endocarditis, real-world records showed. (Heart)

Massive left ventricular hypertrophy is associated with adverse events in children with HCM but does tend to regress. (Circulation)

A small pilot study showed promise for the InVera infusion device for nonthermal catheter-based treatment of chronic venous disease, the manufacturer said.

In immune checkpoint inhibitor-associated myocarditis, myocardial PD-L1 up-regulation indicated greater disease severity and was prognostic for major adverse cardiotoxic events. (JACC: CardioOncology)

Pop singer Zayn Malik disclosed he is currently recovering from an undisclosed illness, but gave credit to his cardiology team. (People)



Source link : https://www.medpagetoday.com/cardiology/generalcardiology/120888

Author :

Publish date : 2026-04-21 19:21:00

Copyright for syndicated content belongs to the linked Source.

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