Brain Worm Lesions Mimicking Cancer; Midlife Dementia Marker; Ovarian Reserve and MS

A case report in Emerging Infectious Diseases described multiple brain lesions that initially mimicked metastases in a 60-year-old man in Spain who eventually was diagnosed with neurocysticercosis.

An Alzheimer’s blood test missed more than half of amyloid PET-positive cases in veterans with prior traumatic brain injury who were cognitively unimpaired or had mild cognitive impairment, cross-sectional data showed. (JAMA Neurology)

Sleep fragmentation correlated with amyloid beta deposition in an autopsy study. (Alzheimer’s & Dementia)

Analyses involving six cohorts linked elevated plasma levels of growth differentiation factor 15 (GDF15) in midlife with dementia risk 15 to 25 years later. (Science Advances)

A meta-analysis found that risk estimates for Alzheimer’s disease among APOE4 homozygotes relative to APOE3 homozygotes in the Japanese population were lower than previously thought. (Molecular Neurodegeneration)

Ovarian reserve did not predict disease course in women with multiple sclerosis (MS), retrospective data from Spain showed. (Journal of Neurology, Neurosurgery & Psychiatry)

Researchers identified two phenotypically distinct autism subtypes based on language, intellectual, and adaptive functioning measures in late childhood and adulthood. (Biological Psychiatry: Cognitive Neuroscience and Neuroimaging)

The FDA will hold an advisory committee meeting on July 29 to review deramiocel, an investigational cell therapy for Duchenne muscular dystrophy, Capricor Therapeutics said. In 2025, the FDA rejected a biologics license application for the drug and requested more data.

Former NFL running back Chris Johnson of the Tennessee Titans said he was diagnosed with amyotrophic lateral sclerosis (ALS) at age 39. (AP)

Here’s what happened to a man who found out after 8 years that his Parkinson’s disease diagnosis was wrong. (The Guardian)