Push for Cath Lab Safety; Eplontersen Flops in ATTR-CM; Off-Label Testosterone Risks

A multisociety expert consensus statement calls for wider implementation of enhanced radiation protection devices for cath lab operators. (JACC: Cardiovascular Interventions)

The FDA approved Johnson & Johnson’s Dual Energy Thermocool Smarttouch SF Platform, a radiofrequency and pulsed field energy catheter ablation system.

The world’s first documented single-port robotic mitral valve repair surgery took place at Corewell Health in the Detroit area.

In a randomized noninferiority trial, the YEARS diagnostic algorithm was as safe as a CT pulmonary angiography approach for ruling out acute pulmonary embolism in patients with active cancer. (JAMA)

Among patients with cancer-associated thrombosis on extended apixaban (Eliquis) after at least 6 months of anticoagulation treatment, recurrent blood clots were uncommon but associated with poor short-term survival, according to a post-hoc analysis of the API-CAT trial. (Circulation)

Mesoglycan had mixed results for secondary prevention of superficial vein thrombosis of the legs, a phase II trial suggested. (eClinicalMedicine)

A Dutch trial found that lower anticoagulation targets in extracorporeal membrane oxygenation may be similar to standard doses. (The Lancet)

Eplontersen (Wainua) failed to meet its primary efficacy endpoint of a composite of cardiovascular mortality and recurrent cardiovascular events in the phase III CARDIO-TTRansform trial of patients with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM), Ionis Pharmaceuticals and AstraZeneca announced.

In FINEARTS-HF, finerenone (Kerendia) showed blood pressure-lowering effects in patients with heart failure with mildly reduced or preserved ejection fraction. (JAMA Cardiology)

Off-label testosterone therapy in men without evidence of hypogonadism was linked to cardiovascular risks out to 10 years, according to a retrospective real-world cohort study. (eBioMedicine)

The American Heart Association had soccer fans practice more than 800,000 CPR training compressions across four cities hosting the FIFA World Cup.

A New York student-athlete diagnosed with Wolff-Parkinson-White syndrome is now an advocate for community ECG screening. (New York Post)

Flu vaccines were associated with lower risks of incident atrial fibrillation and multiple cardiovascular outcomes in a target trial emulation study based on retrospective data. (European Heart Journal)

A line between hypertension and oral health could be drawn in older Chinese adults, a cross-sectional study suggested. (Clinical Cardiology)

Cardiac MRI had clinical utility in the diagnosis of pericarditis, according to a retrospective analysis. (Heart)

The oral NLRP3 inhibitor ruvonoflast will be tested in a phase II study after preliminary data suggested that it significantly reduced high-sensitivity C-reactive protein and other inflammatory biomarkers in participants with high atherosclerotic cardiovascular disease risk. (Journal of the American College of Cardiology)

Please enable JavaScript to view the comments powered by Disqus.