Rectal Cancer ‘Crisis’; Smells Like Cancer; Flushing Away Clues to Colon Cancer

Increasing rectal cancer mortality in millennials has become a “medical crisis.” (NBC News)

Patients with suspicious lung nodules and a history of treatment with SGLT2 inhibitor diabetes drugs had a lower likelihood of nodule progression and need for surgery. (Lung Cancer)

Updated cervical cancer screening guidance from the American College of Obstetricians and Gynecologists endorsed at-home specimen collection by average-risk patients to detect high-risk human papillomavirus infection.

Closure of one of the last remaining radiation clinics in the Mississippi Delta would force some patients to drive as much as 2 hours each way for radiation therapy. (Mississippi Free Press)

Cancer-sniffing dogs diagnosed seven types of early-stage cancer with greater than 90% accuracy. (Dognosis)

Spanish investigators found evidence that epigenetic changes caused by diet, tobacco, and exposure to pesticides may drive development of colorectal cancer in younger people. (Vall d’Hebron Institute of Oncology)

A liquid biopsy accurately predicted whether patients with high-risk early breast cancer would respond to immunotherapy. (Vanderbilt University Medical Center)

Exercise and ibuprofen both showed some potential to offset adverse cognitive effects of cancer treatment. (Cancer)

The incidence and mortality of endometrial cancer continue to increase, but diagnosis, risk stratification, and precision treatment have improved. (Roswell Park Comprehensive Cancer Center)

The FDA rejected an artificial intelligence (AI) developer’s request to bypass formal review of AI-enabled radiology devices in lieu of internal safeguards and postmarket review. (ASCO AI in Oncology)

A survey of U.S. adults showed that the public’s comfort level with use of AI in healthcare has declined. (Ohio State University Wexner Medical Center)

AI-assisted analysis of gene activity in individual cells may offer the potential to identify specific cells associated with cancer survival, which could inform development of more effective treatment. (Oregon Health & Science University)

How many people are flushing away early clues to colon cancer in their bowel movements? (Business Insider)

An investigational camera system has shown potential to help surgeons determine whether cancer has spread to lymph nodes. (Optics)

A monoclonal antibody targeting galectin-9, combined with azacitidine or decitabine, showed preliminary evidence of activity in heavily pretreated relapsed/refractory myelodysplastic syndrome, and in relapsed/refractory acute myeloid leukemia when also combined with venetoclax (Venclexta), PureTech Health announced.

Adding the glycogen synthase kinase-3 beta inhibitor elraglusib to chemotherapy improved median overall survival in untreated metastatic pancreatic cancer from 7.2 to 10.1 months. (Nature Medicine)