What Drives Amish Superagers; Parkinson’s Data Flagged; A Look at Childhood Dementia

Researchers identified two genes — WDR12 and HIVEP3 — that appeared to contribute to preserved cognition in elderly Amish superagers. (Alzheimer’s & Dementia)

Mentally passive sedentary behavior like watching TV appeared to be linked with higher dementia incidence in the Swedish National March Cohort, but findings were not significant after adjustment. (American Journal of Preventive Medicine)

Hormonal contraception was not associated with an increased prevalence of idiopathic intracranial hypertension, according to a meta-analysis. (Neurology)

The authors of two highly cited gut-brain studies — including one on the microbiome’s influence in Parkinson’s disease published in Cell and one on anxiety published in Nature — are working to correct data duplication flagged on PubPeer. (The Transmitter)

Functional independence 90 days after thrombectomy for acute ischemic stroke was similar among patients who received early versus delayed extubation in the EDESTROKE trial. (JAMA Neurology)

The FDA approved a new high-dose regimen of nusinersen (Spinraza) for spinal muscular atrophy, Biogen said.

Serenity Medical said it received FDA humanitarian device exemption approval for its River cerebral venous stent to treat severe, refractory idiopathic intracranial hypertension.

An analysis identified quality gaps in online media coverage of anti-amyloid monoclonal antibody treatments for Alzheimer’s disease. (JAMA Network Open)

Nearly half of published phase III Alzheimer’s clinical trials from 1997 to 2023 did not report patient race or ethnicity, a review showed. (JAMA Network Open)

The American Academy of Neurology issued guidance about the use of smart watches, fitness trackers, and other wearable devices for neurologic care. (Neurology)

The Times shared insights from a family with a 2-year-old girl with Sanfilippo syndrome (mucopolysaccharidosis type III), sometimes referred to as childhood dementia.

Singer Celine Dion, who was diagnosed with stiff-person syndrome, announced her return to the stage after a 6-year hiatus. (The Guardian)